报告题目：Metal-Polyphenol Coordination Nanomaterials for Cancer Therapy

报告人：代云路（澳门大学教授）

报告时间：2020年11月30日（星期一）上午10:00-12:00

报告地点：学院阳光科技楼二楼报告厅

报告摘要：

Metal polyphenols networks (MPNs), which make use of the coordination between metal ions and phenolic molecules, have emerged as promising materials for nanomedicine. Compared with other materials, MPNs have several potential advantages, including pH responsiveness, negligible cytotoxicity, and rapid preparation. Additionally, the phenolic groups in the materials can be functionalized to meet specific applications. We constructed a serious of polyphenol-based nanomaterials for cancer theranostics. These nanoparticles were stable under normal physiological environment and release theraputic agents in the tumor site, which can reduce side effect of theraputic agents to normal organs and enhance treatment efficacy. The nanoparticles can also inhibit the tumor growth and prolong the mice survival time with a low dose of drugs. The polyphenol-based theranostics nanoplatforms establish a novel promising strategy for cancer treatment.

报告人简介：

Dr. Yunlu Dai is an assistant professor in the Faculty of Health Sciences, University of Macau. He received his PhD degree in 2014 from Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences under the supervision of Prof. Jun Lin. Then he moved to the University of Melbourne as a research fellow with Prof. Frank Caruso. In 2016, he joined Dr. Xiaoyuan (Shawn) Chen’s Laboratory in National Institutes of Health (NIH) as a postdoctoral. He initiated his independent research program in 2018 at University of Macau. His research focuses on the multifunctional hybrid nanomaterials for cancer theranostics.