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姓 名： | 林子俺 |
| 性 别： | 男 | |
| 职 称： | 研究员/博导 |
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| 学 历： | 博士 |
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| 职 务： | 副院长、副主任 | |
| 电 话： | ||
| 专 业： | 分析化学 |
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| 电子邮件： | zianlin@fzu.edu.cn |
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| 研究方向： | 生物分离分析/材料分析化学 |
教育背景：
1995.9-1998.7 学院化学系 工业分析
2002.9-2004.7 学院化学化工学院 分析化学（硕士）
2004.9-2007.7 学院化学化工学院 分析化学（直接攻读博士）
工作经历：
2007.7-2009.6 南开大学皇冠国际体育app 博士后 （合作导师：张玉奎院士）
2009.7-至今 学院化学化工学院/食品安全分析与检测教育部重点实验室
2014.9-2015.8 香港浸会大学理学院/化学系 博士后 （合作导师 蔡宗苇教授）
2017.7-2017.9 香港浸会大学理学院/环境与生物分析国家重点实验室 高级访问教授
2010年12月 晋升副研究员
2015年6月 破格获博士生导师资格
2016年7月 正常晋升研究员
教学简介 先后承担研究生《高等分析化学》、《食品安全》，《现代药物分析》、《色谱新技术及其应用》、《药物综合实验》；本科生《分析化学与仪器分析》、《分析化学基础实验》、《仪器分析实验》以及《教授导论讲座》等教学工作。
科研简介 林子俺，男，1977年1月出生，研究员、博士生导师；皇冠国际体育app副院长、食品安全与生物分析教育部重点实验室副主任；《色谱》、《Journal of Analysis and Testing》期刊青年编委、《分析实验室》、《General Chemistry》、《Chinese Chemical Letter》期刊编委；福建省百千万人才工程、福建省高层次C类人才、省高校新世纪人才、泉州市高层次人才（第二层次）、福州青年科技奖和学院杰出青年教师奖获得者。
课题组长期从事复杂样品前处理、色谱、生物质谱基础理论及新技术开发研究。先后主持包括国家自然科学基金（22274021、21974021、21675025、21375018、21005018）在内的20多项科研项目，作为核心骨干参与国家基金委重点研究计划、科技部重点研究计划、国家基金委重大研究计划集成项目、山东省重点研究计划等项目的研究。2016年和2020年分获中国分析测试协会科学技术一等奖和特等奖。迄今，以第一或通讯作者身份发表SCI论文120余篇，包括J. Am. Chem. Soc., Adv. Mater., Mass Spec. Rev., Anal. Chem., Chem Eng J., J. Hazard. Mater., ACS Sustain. Chem. Eng., ACS Appl. Mater. Interfaces, Chem. Commun.,等化学/材料学科国际权威期刊，他引4500余次，H-index 37，3篇论文入选高被引，多篇论文入选热点或封面文章，授权国家发明专利13项。
Research ID：http://www.researcherid.com/rid/C-3506-2011
代表性论文1. Zian Lin, Zenghong Xie*, Haixia Lv, Xucong Lin, Xiaoping Wu, Guonan Chen*; On-Column Coaxial Flow Chemiluminescence Detection for Underivatized Amino Acids by Pressurized Capillary Electrochromatography Using a Monolithic Column. Anal. Chem, 2006, 78(15), 5322-5328.
2. Zian Lin, Xiaoping Wu, Xucong Lin, Zenghong Xie*; End-column chemiluminescence detection for pressurized capillary electrochromatographic analysis of norepinephrine and epinephrine. J. Chromatogr. A 2007, 1170(1-2), 118-121.
3. Zian Lin, Zenghong Xie*, Jian Lin, Xucong Lin, Xiaoping Wu; Evaluation of band broadening in chemiluminescence detection coupled to pressurized capillary electrochromatography with an off-column coaxial flow interface. Electrophoresis 2008, 29(2), 401-409.
4. Zian Lin*, Zenghong Xie; Direct determination of amino acids by pressurized capillary electrochromatography with chemiluminescence detection. J. Sep. Sci, 2008, 31(15), 2852-2859.
5. Zian Lin*, Fan Yang, Xiwen He, Xiaomiao Zhao, Yukui Zhang; Preparation and evaluation of a macroporous molecularly imprinted hybrid silica monolithic column for selective recognition of proteins by high performance liquid chromatography J. Chromatogr. A 2009, 1216(49), 8612-8622.
6. Zian Lin*, Fan Yang, Xiwen He, Yukui Zhang; Organic-inorganic hybrid silica as supporting matrices for specific recognition of bovine hemoglobin via covalent immobilization. J. Sep. Sci, 2009, 32(22), 3980-3987.
7. Zian Lin, Jianhua Zhang, Huimin Cui, Lan Zhang, Guonan Chen*; Determination of aromatic amines in environmental water sample by hollow fiber-liquid phase microextraction and microemulsion electrokinetic chromatography. J. Chromatogr. A 2010, 1217(26), 4507-4510.
8.Tiemei Li, Zian Lin*, Guonan Chen, Lan Zhang*; Controllable Preferential-etching Synthesis of ZnO Nanotubes Array on SiO2 Substrate for Solid-phase Microextraction. Analyst, 2010, 135(10), 2694-2699.
9. Zian Lin, Jianhua Zhang, Huimin Cui, Lan Zhang, Guonan Chen*; Determination of six phthalate esters in soil by microemulsion electrokinetic chromatography coupled with accelerated solvent extraction. J. Sep. Sci, 2010, 33(23-24), 3717-3725.
10. Zian Lin,* Jiangnan Zheng, Fen Lin, Lan Zhang, Zongwei Cai, Guonan Chen*; Synthesis of Magnetic Nanoparticles with Immobilized Aminophenylboronic Acid for Selective capture of Glycoproteins. J. Mater. Chem., 2011, 21(2), 518-524.
11. Zian Lin*, Jilei Pang, Yao Lin, Hui Huang, Zongwei Cai, Lan Zhang*, Guonan Chen; Preparation and evaluation of phenylboronate affinity monolith for selective capture of glycoproteins by capillary liquid chromatography. Analyst, 2011, 136(16), 3281-3288.
12. Zian Lin*, Jilei Pang, Huanghao Yang, Zongwei Cai, Lan Zhang*, Guonan Chen; One-pot synthesis of an organic-inorganic hybrid affinity monolithic column for specific capture of glycoproteins. Chem. Commun., 2011, 47 (34), 9675-9677. (selected as the top 10 articles)
13. Zongbao Chen, Zian Lin*, Yan Cai, and Lan Zhang*. Analysis of plant hormones by microemulsion electrokinetic capillary chromatography coupled with on-line large volume sample stacking. Analyst, 2012, 137(7), 1723-1729.
14. Zian Lin*, Hui Huang, Xiaobo Sun, Yao Lin, Lan Zhang, Guonan Chen. Monolithic column based on a poly(glycidyl methacrylate -co-4-vinylphenylboronic acid-co-ethylene dimethacrylate) copolymer for capillary liquid chromatography of small molecules and proteins. J. Chromatogr. A 2012, 1246, 90-97.
15. Zian Lin*, Jiangnan Zheng, Zhiwei Xia, Huanghao Yang, Lan Zhang,* Guonan Chen. One-pot synthesis of phenylboronic acid-functionalized core-shell magnetic nanoparticles for selective enrichment of glycoproteins. RSC Adv., 2012, 2(12), 5062-5065.
16. Hui Huang, Zian Lin*, Yao Lin, Xiaobo Sun, Yanyan, Xie, Lan Zhang, Guonan Chen. Preparation and evaluation of poly(4-vinylphenylboronic acid-co-pentaerythritol triacrylate) monolithic column for capillary liquid chromatography of small molecules and proteins. J. Chromatogr. A 2012, 1251, 82-90.
17. Zian Lin*, Zhiwei Xia, Jiangnan Zheng, Duo Zheng, Lan Zhang, Huanghao Yang* Guonan Chen. Synthesis of uniformly sized molecularly imprinted polymer-coated silica nanoparticles for selective recognition and enrichment of lysozyme. J. Mater. Chem., 2012, 22(34), 17914-17922.
18. Zian Lin*, Xiaobo Sun, Yao Lin, Guonan Chen*. Highly sensitive analysis of four hemeproteins by dynamically-coated capillary electrophoresis with chemiluminescence detector using an off-column coaxial flow interface. Analyst, 2013, 138 (8), 2269-2278.
19. Zian Lin,* Yao Lin, Xiaobo Sun, Huanghao Yang, Lan Zhang,* Guonan Chen. One-Pot Preparation of a Molecularly Imprinted Hybrid Monolithic Capillary Column for Selective Recognition and Enrichment of Lysozyme. J. Chromatogr. A 2013, 1284, 8-16.
20. Zian Lin*, Hui Huang, Shihua Li, Juan Wang, Xiaoqing Tan, Lan Zhang, Guonan Chen*. Preparation of phenylboronic acid-silica hybrid monolithic column with one-pot approach for capillary liquid chromatography of biomolecules. J. Chromatogr. A 2013, 1271(1), 115-123.
21. Zhiwei Xia, Zian Lin,* Yun Xiao, Ling Wang, Jiangnan Zheng, Huanghao Yang* and Guonan Chen. Facile synthesis of polydopamine-coated molecularly imprinted silica nanoparticles for protein recognition and separation. Biosens. Bioelectron., 2013,47, 120-126.
22. Jintian Cheng, Xiadi Chen, Yimin Cai, Yu He, Zongbao Chen, Zian Lin*, Lan Zhang* Preparation and evaluation of a hydrophilic poly(2-hydroxyethyl methacrylate-co-N,N'-methylene bisacrylamide) monolithic column for pressurized capillary electrochromatography. Electrophoresis 2013, 34(8), 1189-1196.
23. Cheng Zheng, Xiaolong Zhang, Wei Liu, Bo Liu, Huanghao Yang*, Zian Lin*, and Guonan Chen; A selective artificial enzyme inhibitor based on nanoparticle-enzyme interactions and molecular imprinting. Adv. Mater, 2013, 25(41), 5922-5927.
24. Zian Lin,* Juan Wang, Xiaoqing Tan, Lixiang Sun, Ruifang Yu, Huanghao Yang, Guonan Chen. Preparation of boronate-functionalized molecularly imprinted monolithic column with polydopamine coating for glycoprotein recognition and enrichment. J. Chromatogr. A 2013, 1319, 141-147. (Featured by <NewsRX> as “Hot article” ) 医药健康媒体NewsRx专题报道
25. Zian Lin*, Xiaobo Sun, Wenli Hu, Yuqing Yin, Guonan Chen* Sensitive determination of positional isomers of benzenediols in human urine by boronate affinity capillary electrophoresis with chemiluminescence detection. Electrophoresis 2014, 35(7), 993–999. (Invited article)
26. Zian Lin,* Lixiang Sun, Wei Liu, Zhiwei Xia, Huanghao Yang,* Guonan Chen. Synthesis of boronic acid-functionalized molecularly imprinted silica nanoparticle composites for glycoprotein recognition and enrichment. J. Mater. Chem. B, 2014, 2 (6), 637 - 643. (Selected as HOT article and featured on JMCB blog)
27. Zian Lin,* Yun Xiao, Ling Wang, Yuqing Yin, Jiangnan Zheng, Huanghao Yang,* and Guonan Chen. Facile synthesis of enzyme-inorganic hybrid nanoflowers and their application as an immobilized trypsin reactor for highly efficient protein digestion. RSC Adv., 2014, 4 (27), 13888 – 13891.
28. Jiangnan Zheng, Yun Xiao, Ling Wang, Zian Lin,* Huanghao Yang, Lan Zhang,* Guonan Chen. Click synthesis of glucose-functionalized hydrophilic magnetic mesoporous nanoparticles for highly selective enrichment of glycopeptides and glycans J. Chromatogr. A 2014, 1358, 29-38.
29. Zian Lin*, Juan Wang, Xiaofei Yin, Xiaoqing Tan, Ling Wang, Lan Zhang, Guonan Chen. Polymer monolithic capillary column fabricated by using monodisperse iron oxide nanocrystal template to enhance the electrochromatographic separation of small molecules. Electrophoresis 2014, 35(14), 1947-1955.
(30) Zian Lin*, Xiaoqing Tan, Ruifang Yu, Jiashi Lin, Xiaofei Yin, Juan Wang, Lan Zhang*, Huanghao Yang. One-pot preparation of glutathione-silica hybrid monolith for mixed-mode capillary liquid chromatography based on “thiol-ene” click chemistry. J. Chromatogr. A 2014, 1355, 228-237.
(31) Zian Lin*, Yun Xiao, Yuqing, Yin, Wenli Hu, Wei Liu, Lan Zhang, Huanghao Yang*. Facile Synthesis of Enzyme-Inorganic Hybrid Nanoflowers and Its Application as a Colorimetric Platform for Visual Detection of Hydrogen Peroxide and Phenol. ACS Appl. Mater. Interfaces, 2014, 6 (13), 10775–10782.
(32) Jiangnan Zheng, Zian Lin,* Wei Liu, Ling Wang, Sen Zhao, Huanghao Yang, and Lan Zhang*. One-pot synthesis of CuFe2O4 magnetic nanocrystal clusters for highly specific separation of histidine-rich proteins. J. Mater. Chem. B, 2014, 2 (37), 6207 – 6214.
(33) Zhiming Yan, Jiangnan Zheng, Jinfeng Chen, Ping Tong, Minghua Lu, Zian Lin*, Lan Zhang*, Preparation and evaluation of silica-UIO-66 composite as liquid chromatographic stationary phase for fast and efficient separation. J. Chromatogr. A 2014, 1366, 45-53.
(34) Ruifang Yu, Wenli Hu, Guo Lin, Qi Xiao, Jiangnan Zheng, and Zian Lin*. One-pot synthesis of polymer monolithic column by combination of free radical polymerization and azide-alkyne cycloaddition “click” reaction and its application in capillary liquid chromatography RSC Adv., 2015, 5(13), 9828–9836.
(35) Zian Lin*, Juan Wang, Ruifang Yu, Xiaofei Yin, Yu He*. Incorporation of graphene oxide nanosheets into boronate-functionalized polymeric monolith to enhance the electrochromatographic separation of small molecules Electrophoresis, 2015, 36(4), 596-606.
(36) Zian Lin*, Ruifang Yu, Wenli Hu, Jiangnan Zheng, Ping Tong, Hongzhi Zhao and Zongwei Cai.* Preparation of a poly (3'-azido-3'-deoxythymidine-co- popargylmethacrylate-co-pentaerythritol triacrylate) monolithic column by in situ polymerization and click reaction for capillary liquid chromatography of small molecules and proteins. Analyst, 2015, 140(13), 4626 – 4635.
(37) Yuqing Yin#, Yun Xiao#, Guo Lin, Qi Xiao, Zian Lin*, Zongwei Cai. Enzyme-inorganic hybrid nanoflowers based immobilized enzyme reactor with enhanced enzymatic activity. J. Mater. Chem. B, 2015, 3(11), 2295 – 2300 （Highlighted on outside back cover）
(38) Jiangnan Zheng, Zian Lin,* Guo Lin, Huanghao Yang and Lan Zhang* Preparation of magnetic metal-organic framework nanocomposites for highly specific separation of histidine-rich proteins. J. Mater. Chem. B, 2015, 3(10), 2185 – 2191.
(39) Zhiming Yan, Wenmin Zhang, Jia Gao, Yifen Lin, Zian Lin*, Lan Zhang* Reverse-phase high performance liquid chromatography separation of positional isomers on the MIL-53(Fe) packed column. RSC Advances 2015, 5(50), 40094-40102.
(40) Zian Lin*, Jiangnan Zheng, Wei Bian, and Zongwei Cai* CuFe2O4 magnetic nanocrystal clusters as a matrix for the analysis of small molecules by negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Analyst, 2015, 140(15), 5287 – 5294.
(41) Zian Lin, Wei Bian, Jiangnan Zheng, and Zongwei Cai* Magnetic metal-organic framework nanocomposites for enrichment and direct detection of small molecules by negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Chem. Commun., 2015, 51(42), 8785-8788.
(42) Wei Liu, Jiangnan Zheng, Shihua Li, Ruirui Wang, Zian Lin* and Huanghao Yang* Aluminium glycinate functionalized silica nanoparticles for highly specific separation of phosphoproteins. J. Mater. Chem. B, 2015, 3(31), 6528 – 6535.
(43) Zian Lin, Jiangnan Zheng, Guo Lin, Zhi Tang, Xueqing Yang, and Zongwei Cai* Negative ion laser desorption/ionization time-of-flight mass spectrometric analysis of small molecules using graphitic carbon nitride nanosheet matrix. Anal. Chem., 2015, 87 (15), 8005–8012.
(44) Shihua Li, Ling Wang, Sen Zhao, Jinjin Lin, Jiangnan Zheng, and Zian Lin* Preparation of phenyl group-functionalized magnetic mesoporous silica microspheres for fast separation and selective enrichment of peptides. J. Sep. Sci. 2015, 38(22), 3954-3960.
(45) Lixiang Sun, Danhong Lin, Guowei Lin, Ling Wang, and Zian Lin*. Click synthesis of boronic acid- functionalized molecularly imprinted silica nanoparticles with polydopamine coating for enrichment of trace glycoprotein. Anal. Methods, 2015, 7(23), 10026 – 10031.
(46) Yuqing Yin, Chenling Gao, Qi Xiao, Guo Lin, Zian Lin,* Zongwei Cai and Huanghao Yang, Protein-Metal Organic Framework Hybrid Composites with Intrinsic Peroxidase-like Activity as a Colorimetric Biosensing Platform. ACS Appl. Mater. Interfaces, 2016, 8 (42), 29052-29061
(47) Haojiang Wang, Wenli Hu, Qiong Zheng, Wei Bian* and Zian Lin*, One-pot preparation of mercaptotetrazole-silica hybrid monoliths via thiol-ene click reaction for mixed-mode capillary liquid chromatography. J. Sep. Sci. 2017, 40(11), 2344-2354.
(48) Yanting He, Wei Liu, Qi Xiao, Guo Lin, Lei Chen, Chenling Gao, and Zian Lin*. Facile synthesis of Ti4+-immobilized affinity silica nanoparticles for highly selective enrichment of intact phosphoproteins. J. Sep. Sci. 2017, 40(7), 1516–1523
(49) Guo Lin, Chaohong Gao, Qiong Zheng, Zhixian Lei, Zian Lin,* Huanghao Yang and Zongwei Cai* Room-temperature synthesis of core-shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins. Chem. Commun., 2017, 53(26), 3649-3652. (Highlighted on inside back cover) Most downloaded articles of 2017: Organic and Biological Chemistry (1)
50. Chaohong Gao#, Guo Lin#, Qiong Zheng, Zhixian Lei, Jiashi Lin, and Zian Lin,* Facile Synthesis of Core-shell Structured Magnetic Covalent Organic Framework Composite Nanospheres for Selective Enrichment of Peptides with Simultaneous Exclusion of Proteins. J. Mater. Chem. B 2017, 5(36), 7496-7503. (Highlighted on outside back cover)
(51) Zian Lin, and Zongwei Cai*, Negative ion laser desorption/ionization time‐of‐flight mass spectrometric analysis of small molecules by using nanostructured substrate as matrices. Mass Spec. Rev. 2018, 37(5), 681-696.（Cover Page）
52. Lei Chen, Yanting He, Zhixian Lei, Chenling Gao, Qing Xie, Ping Tong, and Zian Lin*, Core-shell structured magnetic covalent organic frameworks for magnetic solid-phase extraction of bisphenols from human serum sample. Talanta, 2018, 181, 296-304.
53. Zhixian Lei, Chenling Gao, Lei Chen, Yanting He, Wende Ma, and Zian Lin.* Recent advances in biomolecule immobilization based on self-assembly: organic-inorganic hybrid nanoflowers and metal-organic frameworks as novel substrates. J. Mater. Chem. B 2018, 6, 1581-1594. （invited article）
54. Lei Chen, Mingyue Zhang, Fengfu Fu, Jingguang Li, Zian Lin.* Facile synthesis of magnetic covalent organic framework nanobeads and application to magnetic solid-phase extraction of trace estrogens from human urine. J. Chromatogr. A 2018, 1567, 136-146.
55. Zian Lin,* Jie Wu, Yongqiang Dong, Peisi Xie, Yanhao Zhang, and Zongwei Cai.* Nitrogen and Sulfur Co-doped Carbon Dots-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Imaging for Profiling Bisphenol S Distribution in Mouse Tissues. Anal. Chem., 2018, 90(18), 10872-10880.
56. Yanting He, Jing Bai, Zian Lin,* Molecular imprinting for protein recognition: current status, challenges and applications. Chin. Sci. Bull., 2019, 64(13), 1392-1406
57. Chaohong Gao, Jing Bai, Yanting He, Qiong Zheng, Wende Ma, Zhixian Lei, Mingyue Zhang, Jie Wu, Fengfu Fu, Zian Lin*. Postsynthetic functionalization of Zr4+ immobilized core-shell structured magnetic covalent organic frameworks for selective enrichment of phosphopeptides. ACS Appl. Mater. Interfaces, 2019, 11 (14), 13735–13741
58. Yanhao Zhang, Yuanyuan Song, Jie Wu, Ruijin Li, Di Hu, Zian Lin* and Zongwei Cai*. Magnetic covalent organic framework as adsorbent and new matrix for enrichment and rapid determination of PAHs and their derivatives in PM2.5 by surface-assisted laser desorption/ionization-time of flight-mass spectrometry Chem. Commun., 2019, 55(26), 3745-3748.
59. Yanxia Li, Hongna Zhang, Yiting Chen, Lu Huang, Zian Lin* and Zongwei Cai*. Core-shell Structured Magnetic Covalent Organic Framework Nanocomposites for Triclosan and Triclocarban Adsorption. ACS Appl. Mater. Interfaces, 2019, 11(25), 22492-22500
60. Chaohong Gao, Jing Bai, Yanting He, Qiong Zheng, Wende Ma, and Zian Lin*. Post-Synthetic Modification of Phenylboronic Acid-Functionalized Magnetic Covalent Organic Frameworks for Specific Enrichment of N-Linked Glycopeptides. ACS Sustain. Chem. Eng., 2019, 7(23), 18926-18934
61. Yu He#, Wenjing Guo#, Kailong Luo, Qianqian Sun, Zian Lin*, Zongwei Cai*. Poly-L-lysine-based tissue embedding compatible with matrix-assisted laser desorption ionization-mass spectrometry imaging analysis of dry and fragile aristolochia plants. J. Chromatogr. A, 2019, 1608, 460389.
62. Jie Wu, Dan Ouyang, Yanting He, Hang Su, Baichuan Yang, Jing Li, Qianqian Sun, Zian Lin,* and Zongwei Cai*. Synergistic Effect of Metal-Organic Framework/Gallic Acid in Enhanced Laser Desorption/lonization Mass Spectrometry. ACS Appl. Mater. Interfaces, 2019, 11(41), 38255-38264.
63. Wende Ma, Qiong Zheng, Yanting He, Guorong Li, Wenjing Guo, Zian Lin*, and Lan Zhang* Size-controllable Synthesis of Uniform Spherical Covalent Organic Frameworks at Room Temperature for Highly Efficient and Selective Enrichment of Hydrophobic Peptides. J. Am. Chem. Soc., 2019, 141, (45), 18271-18277. （高被引）
64. Dan Ouyang, Kailong Luo, Wende Ma, Jie Wu, Jing Li, Yanting He, Zongwei Cai and Zian Lin* A Spherical Covalent-Organic Framework for Enhancing Laser Desorption/Ionization Mass Spectrometry of Small Molecules. Analyst, 2020, 145(8), 3125 - 3130
65. Chao Zhong#, Zhixian Lei#, Huan Huang, Mingyue Zhang, Zongwei Cai and Zian Lin.* One-Pot Synthesis of Trypsin-Based Magnetic Metal-Organic Frameworks for Highly Efficient Proteolysis. J. Mater. Chem. B 2020, 8(21), 4642-4647
66. Qianqian Sun, Chaohong Gao, Wende Ma, Yanting He, Jie Wu, Kailong Luo, Dan Ouyan, Zian Lin,* and Zongwei Cai* Rapid and high-throughput screening of bisphenols in pharmaceuticals and personal care products by using magnetic covalent organic frameworks as a mass spectrometry probe Microchimica Acta 2020, 187(7), 370. (1-11)
67. Mingyue Zhang, Jing Li, Wende Ma, Chao Zhang, Zhifeng Wu, Jingguang Li, Fengfu Fu* and Zian Lin* In-situ synthesis of fluorinated magnetic covalent organic frameworks for fluorinated magnetic solid-phase extraction of ultratrace perfluorinated compounds from milk J. Chromatogr. A, 2020, 1615, 460773.
68. Kailong Luo, Baichuan Yang, Wenjing Guo, Qianqian Sun, Dan Ouyang, Zian Lin* and Zongwei Cai* Surface-Enhanced Laser Desorption/Ionization Mass Spectrometry for Rapid Analysis of Organic Environmental Pollutants by Using Polydopamine Nanospheres as Substrate. Analyst, 2020, 145(16), 5664-5669.
69. Yibing Liu, Wende Ma, Yanting He, Zhuling Chen,* and Zian Lin* Facile synthesis of hydrophilic magnetic mesoporous silica microspheres for selective enrichment of glycopeptides and glycans. Anal. Lett, 2020, 54(6), 966-978.
70. Mingyue Zhang, Xi Yan, Wende Ma, Yu He, Zongwei Cai, Zian Lin* Facile synthesis of tubular magnetic fluorinated covalent organic frameworks for efficient enrichment of ultratrace polybrominated diphenyl ethers in environmental samples. Talanta 2021, 221, 121651.
71. Chao Zhong,# Baichuan Yang,# Weini Huang, Huan Huang, Shasha Zhang, Xi Yan, Qiaomei Lu, Zhuling Chen, and Zian Lin* Self-assembly synthesis of trypsin-immobilized monolithic microreactor for fast and efficient proteolysis J. Chromatogr. A, 2021,1635, 461742
72. Juan Lin, Chao Zhong, Qiaomei Lu, and Zian Lin*. Room-temperature Synthesis of Trypsin-inorganic Hybrid Nanocomposites for Fast and Efficient Protein Digestion. ChemistrySelect 2020, 5(40), 12500-12504
73. Wenjing Guo, Wenli Wang, Yixin Yang, Shasha Zhang, Baichuan Yang, Wende Ma, Yu He, Zian Lin,* Zongwei Cai* Facile fabrication of magnetic covalent organic frameworks and their application in selective enrichment of polychlorinated naphthalenes from fine particulate matter. Microchimica Acta 2021, 188(3), 91 1-10
74. Jing Li, Yixin Yang, Wende Ma, Guorong Li, Qiaomei Lu, and Zian Lin* One-Pot Room-Temperature Synthesis of Covalent Organic Framework-Coated Superhydrophobic Sponges for Highly Efficient Oil-Water Separation. J. Hazard. Mater., 2021,411, 125190.
75. Yanting He, Qiong Zheng, and Zian Lin* Ti4+-Immobilized Hierarchically Porous Zirconium-Organic Frameworks for Highly Efficient Enrichment of Phosphopeptides Microchimica Acta 2021, 188(5), 150 1-11
76. Qianqian Sun, Shangshang Zhang, Weini Huang, Ran Wang, Chen, Zongwei Cai, and Zian Lin* 4-Mercaptobenzoic acid as a MALDI matrix for highly sensitive analysis of metals. Analyst, 2021, 146(5), 1543-1547 （Hot article）
77. Qianqian Sun, Wende Ma, Dan Ouyang, Guorong Li, Yixin Yang, Xi Yan, Hang Su, Zian Lin *, and Zongwei Cai * Thiol functionalized covalent organic frameworks for highly selective enrichment and detection of mercury by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Analyst, 2021,146(9), 2991-2997.
78. Yanting He, Weini Huang, Qiong Zheng, Huan Huang, Dan Ouyang, Shasha Zhang, Xi Yan, Yin Ji, Yijing Wu, and Zian Lin*. Two-dimensional guanidinium-based covalent organic nanosheets for controllable recognition and specific enrichment of global/multi-phosphopeptides. Talanta, 2021, 233, 122497.
79. Wende Ma, Guorong Li, Chao Zhong, Yixin Yang, Qianqian Sun, Dan Ouyang, Wei Tong, Wenchang Tian, Lan Zhang, and Zian Lin*, Room-Temperature Controllable Synthesis of Hierarchically Flower-like Hollow Covalent Organic Frameworks for Brain Natriuretic Peptide Enrichment. Chem. Commun., 2021, 57, 7362-7365 (Highlighted as outside front cover)（官网封面报道）
80. Huan Huang, Qiong Zheng, Yanting He, Chao Zhong, Wenchang Tian, Shasha Zhang, Juan Lin and Zian Lin* Facile synthesis of bifunctional polymer monolithic column for tunable and specific capture of glycoproteins and phosphoproteins. J. Chromatogr. A, 2021, 1651, 462329
81. Qiong Zheng, Yanting He, Wende Ma, Yijing Wu, Zihan Chen, Ran Wang, Wei Tong, and Zian Lin* Facile Synthesis of Spherical Covalent Organic Frameworks as Stationary Phase for Ultrahigh Performance Liquid Chromatography, Chem. Commun., 2021, 57(61), 7501-7504.（Highlighted as outside back cover）
82. Yanting He, Shasha Zhang, Chao Zhong, Yixin Yang, Guorong Li, Yin Ji, and Zian Lin* Facile Synthesis of Ti4+-Immobilized Magnetic Covalent Organic Frameworks for Highly Efficient Enrichment of Global Phosphopeptides Talanta, 2021, 235, 122789
83. Dan Ouyang, Qiong Zheng, Huan Huang, Zongwei Cai, and Zian Lin* Covalent Organic Framework Nanofilm-Based Laser Desorption/Ionization Mass Spectrometry for 5-Fluorouracil Analysis and Tissue Imaging. Anal. Chem., 2021, 93(47), 15573-15578.
84. Chao Zhong, Wende Ma, Yanting He, Dan Ouyang, Guorong Li, Yixin Yang, Qiong Zheng, Huan Huang, Zongwei Cai, and Zian Lin * Controllable Synthesis of Hollow Microtubular Covalent Organic Frameworks as an Enzyme-Immobilized Platform for Enhancing Catalytic Activity. ACS Appl. Mater. Interfaces, 2021, 13(44), 52417-52424
85. Guorong Li, Wende Ma, Yixin Yang, Chao Zhong, Huan Huang, Dan Ouyang, Yanting He, Wenchang Tian, Juan Lin, and Zian Lin* Nanoscale Covalent Organic Frameworks with Donor-Acceptor Structures as Highly Efficient Light-Responsive Oxidase-like Mimics for Colorimetric Detection of Glutathione. ACS Appl. Mater. Interfaces, 2021, 13(41), 49482-49489.
86. Yixin Yang, Wende Ma, Guorong Li, Chao Zhong, Xi Yan, Weini Huang, Shasha Zhang, Zian Lin,* and Zongwei Cai Polyamide-Supported Covalent Organic Framework Nanomembranes for Molecular Size-dependent Selective Separation. ACS Applied Nano Materials, 2021, 4(12), 13967-13975.
87. Wende Ma, Chao Zhong, Juan Lin, Zhuling Chen, Guorong Li, Wei Tong, Yijing Wu, Lan Zhang, and Zian Lin* Copper(II) ions-Immobilized Virus-Like Hollow Covalent Organic Frameworks for Highly Efficient Capture of Amyloid Beta-Peptide 1-42 Chin. Chem. Lett 2022, 33(12), 5174-5179.
88. Huan Huang, Dan Ouyang, Zian Lin, Recent Advances in Surface-Assisted Laser Desorption/Ionization Mass Spectrometry and its Imaging for Small Molecules Journal of analysis and testing (Invited review) 2022, 6, 217-234. （Cover page，封面文章）
89. Yanting He, Qiong Zheng, Huan Huang, Yin Ji, Chao Zhong, Guorong Li and Zian Lin* Hydrophilic Hollow Zirconium Organic Frameworks Tailored for Simultaneous Recognition and Capture of Phosphorylated and Glycosylated Peptides Anal Chim Acta, 2022, 1198, 339552. （高被引）
90. Qiong Zheng, Jiajia Huang, Yanting He, Huan Huang, Yin Ji, Yongfan Zhang, Zian Lin* Single-Crystalline Covalent Organic Frameworks as High-Performance Liquid Chromatographic Stationary Phases for Positional Isomer Separation ACS Appl. Mater. Interfaces, 2022, 14(7), 9754-9762（入选封面文章）
91. Xi Yan, Yixin Yang, Guorong Li, Jianhua Zhang, Yu He, Ran Wang, Zian Lin*, and Zongwei Cai. Thiophene-based covalent organic frameworks for highly efficient iodine capture. Chin. Chem. Lett, 2023, 34(1), 107201
92. Weini Huang,# Wenya Shao,# Yin Ji, Heming Li, Jiajing Chen, and Zian Lin* Covalent organic frameworks-based solid phase microextraction coupled with ambient mass spectrometry for sensitive screening and quantitative evaluation of carbamazepine and its metabolite in mice Talanta, 2022, 243, 123341
93. Shasha Zhang, Ran Wang, Yijing Wu, Zhuling Chen, Ping Tong, Yu He, Zian Lin*, and Zongwei Cai,* One-Pot Synthesis of Magnetic Covalent Organic Frameworks for Highly Efficient Enrichment of Phthalate Esters from Fine Particulate Matter J. Chromatogr. A, 2022,1667,462906
94. Dan Ouyang, Zhihua Fu, Guorong Li, Chao Zhong, Jiahao Yuan, Huan Huang, Juan Lin, Gang Xu,*and Zian Lin* Highly Reproducible Serum Metabolic Profiles Revealed by Metal–Organic Framework Nanofilm for Precise Diagnosis of Cardiovascular Disease. Chin. Chem. Lett 2023, https://doi.org/10.1016/j.cclet.2022.107992
95. Yanting He, Zian Lin.* Recent advances in protein-imprinted polymers: synthesis, applications and challenges J. Mater. Chem. B, 2022, 10, 6571-6589（Invited review）
96. Guorong Li, Wenchang Tian, Chao Zhong, Yixin Yang, and Zian Lin* Construction of Donor-Acceptor Heteroporous Covalent Organic Frameworks as Photoregulated Oxidase-like Nanozymes for Sensing Signal Amplification. ACS Appl. Mater. Interfaces, 2022, 14(18), 21750–21757
97. Wenya shao, Ying Sun, Hang Su, Qianqian Sun, Zian Lin* 4-mercaptobenzoic acid-assisted laser desorption/ionization mass spectrometry for sensitive quantification of cesium and strontium in drinking water. Rapid Commun Mass Spectrom. 2022,36(17), e9342
98. Yin Ji, Yanting He, Rubing chen, Chao Zhong, Heming Li, Yijing Wu, Zian Lin* Hydrophilic glutathione-modified flower-like hollow covalent organic frameworks for highly efficient capture of N-linked glycopeptides J. Mater. Chem. B, 2022, 10, 6507 - 6513
99. Akang Dan, Shasha Zhang, Zhongliang Chen, Jinghan Dong, Wenjun Zheng, Yuxin Tu, Zian Lin*, Zongwei Cai* Facile synthesis of Cu2+-immobilized magnetic covalent organic frameworks for highly efficient enrichment and sensitive determination of five phthalate monoesters from mouse plasma with HPLC-MS/MS Talanta, 2023,253, 123923
100. Qiong Zheng#, Jin Liu#, Yijing Wu, Yin Ji, and Zian Lin* Fluoro-functionalized Spherical Covalent Organic Frameworks as Liquid Chromatographic Stationary Phase for the High-resolution Separation of Organic Halides Anal. Chem., 2022, 94(51), 18067-18073
101. Jiahao Yuan#, Weini Huang#, Wei Tong, Zihan Chen, Heming Li, Jiajing Chen, and Zian Lin* In-situ growth of covalent organic framework on stainless steel needles as solid-phase microextraction probe coupled with electrospray ionization mass spectrometry for rapid and sensitive determination of tricyclic antidepressants in biosamples J. Chromatogr. A, 2023,1695, 463955
102. Ran Wang, Wei Tong, Yijing Wu, Zhuling Chen, Zian Lin,* and Zongwei Cai,* Facile synthesis of hollow microtubular COF as enrichment probe for quantitative detection of ultratrace quinones in mice plasma with APGC-MS/MS Microchimica Acta 2023, 190, 72.
103. Yixin Yang, Guorong Li, Dan Ouyang, Zongwei Cai, Zian Lin* Dual-activation interfacial polymerization based anionic covalent organic framework nanofiltration membrane for high-flux dye separation Chem Eng J., 2023,456,141008
104. Guorong Li, Yijing Wu, Chao Zhong, Yixin Yang, and Zian Lin* Predesigned Covalent Organic Framework with Sulfur Coordination: Anchoring Au Nanoparticles for Sensitive Colorimetric Detection of Hg(II) Chin. Chem. Lett, 2023 Accepted
105. Zihan Chen, Yijing Wu, Dan Ouyang, Zian Lin* Covalent organic framework film-based laser desorption/ionization mass spectrometry for rapid and sensitive quantification of homocysteine in human serum Rapid Commun Mass Spectrom. 2023,37(5), e9463
106.Chao Zhong, Guorong Li, Wenchang Tian, Dan Ouyang, Yin Ji, Zongwei Cai, and Zian Lin* Construction of Covalent Organic Framework Capsule-based Nanoreactor for Sensitive Glucose Detection ACS Applied Materials & Interfaces 2023, 15, 7, 10158-10165
107. Jiajing Chen, Huan Huang, Dan Ouyang, Jiali Lin, Zhuling Chen, Zongwei Cai, and Zian Lin* Usage of 6-borono-1-methylquinoline-1-ium as a reactive matrix for rapid profiling of cis-diol compounds in food by matrix-assisted laser desorption/ionization mass spectrometry revised
108. Dan Ouyang,‡ Huan Huang,‡ Yanting He, Jiajing Chen, Jiali Lin, Zhuling Chen, Zongwei Cai, and Zian Lin* Utilization of Hydralazine as A Reactive Matrix for Enhanced Detection and On-MALDI-Target Derivatization of Saccharides Chin. Chem. Lett, 2023 Accepted
109. Yixin Yang, Jinghan Dong, Ran Wang, Zian Lin,* Zongwei Cai,* Urchin-like fluorinated covalent organic frameworks decorated fabric for effective self-cleaning and versatile oil/water separation J. Hazard. Mater., minor revised
110. Yin Ji, Heming Li, Jinghan Dong, Jiashi Lin,* Zian Lin* Super-hydrophilic sulfonate-modified covalent organic framework nanosheets for efficient separation and enrichment of glycopeptides J. Chromatogr. A, 2023, doi.org/10.1016/j.chroma.2023.464020
获奖情况
1. 蔡宗苇，林子俺，夏亦荠，洪燕君，朱林，赵超，邵晓剑，张海磊，张宏娜，张岩皓 “环境毒理研究的质谱新方法” 2020年“中国分析测试协会科学技术奖（CAIA奖）特等奖
2. 蔡宗苇，林子俺，卢明华，张建刚，路雯婧，杨雪清，王书娟，沈阳 “基于纳米材料的负离子LDI-MS分析小分子物质的研究” 2016年“中国分析测试协会科学技术奖（CAIA奖）一等奖
申请国家发明专利：
（1）一种有机-无机杂化毛细管整体柱制备方法（ZL201110085266.7）
（2）一锅合成的苯硼酸聚合物磁性纳米复合材料及制备方法（ZL201210000137.8）
（3）一种亲水磁性介孔微球及其制备方法与应用(ZL201310163661.1)
（4）一种疏水磁性介孔微球及其制备方法和应用(ZL201410034003.7)
（5）一种基于Cu(I)点击的聚合物基质毛细管整体柱及其制备方法 (ZL201410132570.6)
（6）一种核苷聚合物基质的毛细管整体柱及其制备方法和应用的制作方法 (ZL201410541150.3)
（7）一种磁性共价有机骨架纳米复合材料及制备方法和应用 (ZL201610246124.7)
（8）一种双功能亲和有机聚合基质毛细管整体柱的制备方法 （ZL2017101304648）
（9）巯基苯并芘磺酸型有机-无机杂化整体柱及制备和应用 （ZL201710206235X）
（10） 巯基衍生化L-脯氨酸型有机-无机杂化整体柱及其制备方法 （ZL2018100125556）
（11）一种球形共价有机骨架材料及其制备方法和应用（ZL2018112685084）
（12） 一种基于表面辅助激光解吸离子化质谱快速检测细菌内毒素的方法 （ZL2019100739459）
（13）一种基于巯基苯甲酸辅助激光解吸离子化质谱快速检测金属离子的方法（ZL2020113977068）
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